The ACTN3 gene encodes the Alpha-actinin protein which is involved in the composition of skeletal muscle.
People normally have two alleles per gene, one inherited from their mother and one inherited from their father.
This allele originates from an ancient Eurasian mutation that occurred thousands of years ago.
This allele has been widespread globally for tens of thousands of years.
It is the combination of a person's pair of gene alleles that influences traits.
The ACTN3 gene is located on chromosome 11 and encodes the protein named "Alpha-actinin-3 (alpha-actin-binding)", which influences the reported traits.
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