The ALDH2 gene encodes an enzyme involved in the processing of alcohol.
People normally have two alleles per gene, one inherited from their mother and one inherited from their father.
This allele has been widespread globally for tens of thousands of years.
This allele originates from an ancient Asian mutation that occurred thousands of years ago.
It is the combination of a person's pair of gene alleles that influences traits.
The ALDH2 gene is located on chromosome 12 and encodes the protein named "Aldehyde dehydrogenase, mitochondrial", which influences the reported traits.
|Genetics Home Reference by the U.S. National Library of Medicine||ALDH2|
|Online Mendelian Inheritance in Man||100650|
|U.S. National Center for Biotechnology Information||217|
- "Ethanol patch test: a simple method for identifying the effectiveness of cyanamide in alcoholics." PMID 10803778
- "Comparison between self-reported facial flushing after alcohol consumption and ALDH2 Glu504Lys polymorphism for risk of upper aerodigestive tract cancer in a Japanese population." PMID 20518787